Statistical methods for linking health, exposure, and hazards
| Autor: | Frances J. Mather, Elizabeth Cullen Langlois, LuAnn E. White, Charles Shorter, Christopher M. Swalm, Jeffrey G. Shaffer, William R. Hartley |
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| Rok vydání: | 2004 |
| Předmět: |
Hazard (logic)
Multivariate statistics Multivariate analysis Computer science Health Toxicology and Mutagenesis Risk Assessment Mini-Monograph: Public Health Tracking Cohort Studies symbols.namesake Health care Statistics Outcome Assessment Health Care Humans data linkage Estimation health outcome data Data collection business.industry Data Collection Public Health Environmental and Occupational Health Reproducibility of Results Markov chain Monte Carlo Environmental exposure Environmental Exposure Articles Models Theoretical GIS United States Bayesian modeling exposure Case-Control Studies Multivariate Analysis symbols Geographic Information Systems statistical methods Environmental Pollutants business Environmental Health Monte Carlo Method hazards Information Systems |
| Zdroj: | Environmental Health Perspectives |
| ISSN: | 0091-6765 |
| Popis: | The Environmental Public Health Tracking Network (EPHTN) proposes to link environmental hazards and exposures to health outcomes. Statistical methods used in case-control and cohort studies to link health outcomes to individual exposure estimates are well developed. However, reliable exposure estimates for many contaminants are not available at the individual level. In these cases, exposure/hazard data are often aggregated over a geographic area, and ecologic models are used to relate health outcome and exposure/hazard. Ecologic models are not without limitations in interpretation. EPHTN data are characteristic of much information currently being collected--they are multivariate, with many predictors and response variables, often aggregated over geographic regions (small and large) and correlated in space and/or time. The methods to model trends in space and time, handle correlation structures in the data, estimate effects, test hypotheses, and predict future outcomes are relatively new and without extensive application in environmental public health. In this article we outline a tiered approach to data analysis for EPHTN and review the use of standard methods for relating exposure/hazards, disease mapping and clustering techniques, Bayesian approaches, Markov chain Monte Carlo methods for estimation of posterior parameters, and geostatistical methods. The advantages and limitations of these methods are discussed. |
| Databáze: | OpenAIRE |
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