Validity, reliability and optimisation of the TOPICOP questionnaire for oral lichen planus
Autor: | Cintia Chamorro-Petronacci, Andrés Blanco-Carrión, Fernando Rodríguez-González, Alejandro I. Lorenzo-Pouso, Abel García-García, Mario Pérez-Sayáns, Pía López-Jornet |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Treatment adherence Prom Anxiety 03 medical and health sciences 0302 clinical medicine stomatognathic system Surveys and Questionnaires medicine Validity reliability Humans General Dentistry Receiver operating characteristic analysis business.industry fungi Reproducibility of Results 030206 dentistry General Medicine medicine.disease Dermatology stomatognathic diseases Phobic Disorders Patient-reported outcome Oral lichen planus medicine.symptom business 030217 neurology & neurosurgery Prolonged treatment Lichen Planus Oral |
Zdroj: | Acta Odontologica Scandinavica. 78:501-508 |
ISSN: | 1502-3850 0001-6357 |
Popis: | Objectives: Due to their anti-inflammatory and immunosuppressive effects, topical corticosteroids (TCs) are commonly used for the treatment of patients with oral lichen planus (OLP) with an erosive or ulcerative component. It has been suggested that many of these patients may suffer from fear or anxiety as a result of prolonged treatment with TCs. The objective of this study was twofold: (1) to optimise a patient reported outcome measure (PROM) in order to explore this feature, and (2) to evaluate this PROM in the treatment of OLP patients.Methods: A group of qualitative researchers adapted the TOPICOP questionnaire in order for it to be used as a PROM for OLP via structural equation modelling (SEM) and internal consistency (IC) analysis. Consequently, 34 patients with symptomatic OLP who were undergoing treatment with TCs completed a questionnaire and underwent a clinical assessment.Results: SEM presented an adequate fit (RMSA = 0.07, CFI = 0.94 and WRMR = 1.18), as well as a high IC (α = 0.81). A total of 16 patients (47.1%) reported TCs phobia. The receiver operating characteristic analysis (ROC) revealed that a TOPICOP value ≥50% predicted the presence of TCs phobia with a sensitivity of 93% and a specificity of 100%.Conclusions: The optimised TOPICOP scale proved valuable as a PROM in OLP. TCs phobia can be a real consideration in OLP, nonetheless, it does not appear to be an impediment to treatment adherence. |
Databáze: | OpenAIRE |
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