Implantation of cigarette smoke condensate in the lungs of Syrian golden hamsters
Autor: | H. Haas, M. B. Ketkar, J. Althoff |
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Rok vydání: | 1979 |
Předmět: |
Adenoma
Male Cancer Research Pathology medicine.medical_specialty Lung Neoplasms Toxicology chemistry.chemical_compound Species Specificity Cricetinae medicine Cigarette smoke Animals Benzopyrenes Lung Metaplasia Hyperplasia Mesocricetus Smoking Sarcoma General Medicine Neoplasms Experimental Oncology Benzo(a)pyrene chemistry Syrian golden hamsters |
Zdroj: | Journal of cancer research and clinical oncology. 94(1) |
ISSN: | 0171-5216 |
Popis: | Different doses of benzo(a)pyrene, cigarette smoke condensate (CSC) and its nitromethane fraction (NMF), in wax pellets, were directly implanted into the lungs of Syrian golden hamsters. Pleomorphic sarcomas were induced in the B(a)P treated animals. Several epithelial proliferative lesions and a few bronchiogenic adenomas were induced in CSC and NMF treated hamsters. A species-specific effect has been observed in this investigation. |
Databáze: | OpenAIRE |
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