Standardized Parenteral Nutrition for the Transition Phase in Preterm Infants: A Bag That Fits
| Autor: | Mairead Kiely, Brendan P. Murphy, Ann-Marie Brennan, Sarah Fenton |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Male Parenteral Nutrition Databases Factual Birth weight Fortification Population nutrient modeling Nutritional Status lcsh:TX341-641 transition phase Article 03 medical and health sciences 0302 clinical medicine Animal science Enteral Nutrition Standardized parenteral nutrition 030225 pediatrics standardized parenteral nutrition amino acids enteral nutrition preterm infants Medicine Weaning Humans Infant Very Low Birth Weight education Infant Nutritional Physiological Phenomena education.field_of_study 030109 nutrition & dietetics Nutrition and Dietetics business.industry Infant Newborn Nutritional Requirements Enteral feeds Preterm infants Transition phase Regimen Parenteral nutrition Gestation Amino acids Female Nutrient modeling business Enteral nutrition lcsh:Nutrition. Foods and food supply Infant Premature Food Science |
| Zdroj: | Nutrients; Volume 10; Issue 2; Pages: 170 Nutrients Nutrients, Vol 10, Iss 2, p 170 (2018) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu10020170 |
| Popis: | The optimal composition of standardized parenteral nutrition (SPN) is not yet known, contributing to nutrient deficit accrual and growth failure, with the period of parenteral nutrition weaning, i.e., transition (TN) phase, being identified as particularly vulnerable. We created a comprehensive nutrition database, representative of the nutritional course of a diverse range of preterm infants (n = 59, birth weight ≤ 1500 g, gestation < 34 weeks) by collecting hourly macronutrient intake data as part of a prospective, observational study over 19 months. Using a nutrient modeling technique for the TN phase, various amino acid (AA) concentrations of SPN were tested within the database, whilst acknowledging the nutritional contribution from enteral feeds until target AA intakes were consistently achieved. From the modeling, the AA composition of SPN was determined at 3.5 g/100 mL, which was the maximum to avoid exceeding target intakes at any point in the TN phase. However, in order to consistently achieve target AA intakes, additional nutritional strategies were required, which included increasing the exclusion of enteral feeds in fluid and nutrient calculations from |
| Databáze: | OpenAIRE |
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