Autor: |
MM Samim, Debjyoti Dhar, Sheetal Goyal, Treshita Dey, Naznin Parvin, Rutul D. Shah, Vikram Singh, Sampurna Chowdhury, Bhavesh Mohan Lal, Nibu Varghese, Abhishek Gohel, Abhishek Chowdhury, Aritra Chatterjee, Shahyan Siddiqui |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Journal of clinical neurology (Seoul, Korea). 18(6) |
ISSN: |
1738-6586 |
Popis: |
Autoimmune encephalitis (AIE) following coronavirus disease 2019 (COVID-19) is an underexplored condition. This study aims to systematically review the clinico-investigational and pathophysiologic aspects of COVID-19 and its vaccines in association with AIE, and identify the factors predicting neurological severity and outcomes.Relevant data sources were searched using appropriate search terms on January 15, 2022. Studies meeting the criteria for AIE having a temporal association with COVID-19 or its vaccines were included.Out of 1,894 citations, we included 61 articles comprising 88 cases: 71 of COVID-19-associated AIE, 3 of possible Bickerstaff encephalitis, and 14 of vaccine-associated AIE.There were 23 definite and 48 possible seronegative AIE cases. Anti-NMDAR (N-methyl-D-aspartate receptor;The study has revealed diagnostic, therapeutic, and pathophysiological aspects of AIE associated with COVID-19 and its vaccines, and its differences from postinfectious AIE.PROSPERO registration number CRD42021299215. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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