Reduction of Environmental Contamination With Multidrug-Resistant Bacteria by Copper-Alloy Coating of Surfaces in a Highly Endemic Setting
| Autor: | Elisabeth Paramythiotou, Irini Mavrou, George Petrikkos, Anastasia Antoniadou, Theofano Panagea, Maria Souli, Maria Drogari-Apiranthitou, Apostolos Armaganidis, Helen Giamarellou, Evangelos Papadomichelakis, Ioannis Katsarolis |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) Staphylococcus aureus Veterinary medicine Epidemiology medicine.drug_class 030106 microbiology Beds 030501 epidemiology Biology medicine.disease_cause Bioburden Random Allocation 03 medical and health sciences Antibiotic resistance Antiseptic Drug Resistance Multiple Bacterial Gram-Negative Bacteria Alloys medicine Humans Equipment and Supplies Hospital Aged Cross-Over Studies Ecology Middle Aged Contamination biology.organism_classification Crossover study Bacterial Load Intensive Care Units Infectious Diseases Enterococcus Fomites Copper alloy Equipment Contamination Female 0305 other medical science Copper |
| Zdroj: | Infection Control & Hospital Epidemiology. 38:765-771 |
| ISSN: | 1559-6834 0899-823X |
| DOI: | 10.1017/ice.2017.52 |
| Popis: | OBJECTIVETo evaluate the efficacy of copper-coating in reducing environmental colonization in an intensive-care unit (ICU) with multidrug-resistant-organism (MDRO) endemicityDESIGNInterventional, comparative crossover trialSETTINGThe general ICU of Attikon University hospital in Athens, GreecePATIENTSThose admitted to ICU compartments A and B during the study periodMETHODSBefore any intervention (phase 1), the optimum sampling method using 2 nylon swabs was validated. In phase 2, 6 copper-coated beds (ie, with coated upper, lower, and side rails) and accessories (ie, coated side table, intravenous [i.v.] pole stands, side-cart handles, and manual antiseptic dispenser cover) were introduced as follows: During phase 2a (September 2011 to February 2012), coated items were placed next to noncoated ones (controls) in both compartments A and B; during phase 2b (May 2012 to January 2013), all copper-coated items were placed in compartment A, and all noncoated ones (controls) in compartment B. Patients were randomly assigned to available beds. Environmental samples were cultured quantitatively for clinically important bacteria. Clinical and demographic data were collected from medical records.RESULTSCopper coating significantly reduced the percentage of colonized surfaces (55.6% vs 72.5%; PP=.003) or by enterococci (4% vs 17%; P=.014), the total bioburden (2,858 vs 7,631 cfu/100 cm2; P=.008), and the bioburden of gram-negative isolates, specifically (261 vs 1,266 cfu/100 cm2; P=.049). This effect was more pronounced when the ratio of coated surfaces around the patient was increased (phase 2b).CONCLUSIONSCopper-coated items in an ICU setting with endemic high antimicrobial resistance reduced environmental colonization by MDROs.Infect Control Hosp Epidemiol 2017;38:765–771 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|