Tumor Size and N2 Lymph Node Metastasis Are Significant Risk Factors for Early Recurrence in Completely Resected Centrally Located Primary Lung Cancer Patients
| Autor: | Hikaru Miyamoto, Nobuhiro Izumi, Takuma Tsukioka, Ryuichi Ito, Hidetoshi Inoue, Noritoshi Nishiyama, Hiroaki Komatsu, T. Kimura |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Lung Neoplasms Time Factors Early Recurrence medicine.medical_treatment Lymph node metastasis Pneumonectomy Risk Factors Carcinoma Non-Small-Cell Lung medicine Humans Postoperative Period Neoplasm Metastasis Lung cancer Pathological Aged Neoplasm Staging Retrospective Studies Aged 80 and over Tumor size business.industry Sleeve Lobectomy General Medicine Middle Aged Prognosis medicine.disease Tumor Burden Oncology Lymphatic Metastasis Resection margin Female Lymph Nodes Radiology Neoplasm Recurrence Local business Follow-Up Studies |
| Zdroj: | Anticancer Research. 41:2165-2169 |
| ISSN: | 1791-7530 0250-7005 |
| Popis: | In centrally-located lung cancer treatment, it is difficult to attain a sufficient resection margin. It is important to investigate recurrent styles in centrally-located lung cancer patients.Primary lung cancer located at the hilar area that requires pneumonectomy or sleeve lobectomy is defined as centrally-located lung cancer. Early recurrence was defined as that within 1 year after surgery.This study included 43 centrally-located lung cancer patients. Ten patients underwent pneumonectomy and 33 underwent sleeve lobectomy. Eleven patients experienced early recurrence. Non-squamous cell carcinoma (p=0.012), tumor size64 mm (p0.001) and pathological N2 (p=0.012) were significant predictors for early recurrence by univariate analysis. Also, tumor size64 mm (p=0.006) and pathological N2 (p=0.019) were independent predictors by multivariate analysis.Non-squamous cell carcinoma, tumor size and pathological N2 were significant predictors of early recurrence in centrally-located lung cancer. The type of surgical procedure did not affect recurrence development. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|