An unusual case of anti-Borrelia burgdorferi immunoglobulin G seroconversion caused by administration of intravenous gammaglobulins
| Autor: | O. Bauraind, S. Mullier, V. Luyasu, M. Dupuis |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Microbiology (medical) Blotting Western Context (language use) Enzyme-Linked Immunosorbent Assay Biology Cross Reactions Immunoglobulin G Serology Humans Avidity Serologic Tests Seroconversion Borrelia burgdorferi False Negative Reactions Lyme Disease Immunization Passive Immunoglobulins Intravenous Gamma globulin General Medicine biology.organism_classification Virology Antibodies Bacterial Treatment Outcome Infectious Diseases Immunoglobulin M Child Preschool Immunology biology.protein Antibody |
| Zdroj: | Clinical Microbiology and Infection. 7(12):697-699 |
| ISSN: | 1198-743X |
| DOI: | 10.1046/j.1469-0691.2001.00337.x |
| Popis: | Administration of gammaglobulins to individuals without specific anti-Borrelia burgdorferi antibodies may lead to immunoglobulin G (IgG) conversion as detected by enzyme-linked immunosorbent assay (ELISA). In some cases however, complementary techniques such as Western blot or avidity will be of prime importance in distinguishing the start of an infection from the passive immunization induced by the gammaglobulins. In all cases, the key element before reaching conclusions in relation to any of these investigations remains the confrontation between the clinical context and the biological findings. This is the scenario that has been followed in our observation. |
| Databáze: | OpenAIRE |
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