A new intracellular flush solution improves renal transplant preservation

Autor:	B. H. Brouhard, P. N. Bretan, A. C. Novick
Rok vydání:	1991
Předmět:	Graft Rejection medicine.medical_specialty business.industry Graft Survival Urology Cyclosporins Ischemic injury Organ Preservation General Medicine Kidney Transplantation Solutions Dogs Renal transplant Reperfusion Injury Renal allograft medicine Animals business Intracellular
Zdroj:	Cleveland Clinic Journal of Medicine. 58:54-58
ISSN:	1939-2869 0891-1150
DOI:	10.3949/ccjm.58.1.54
Popis:	A new renal preservation flush solution (PB-2) has been developed to minimize the ischemic injury processes that occur during hypothermic storage and reperfusion and that can decrease renal viability and survival. Development of the new formulation took into account the intracellular and biological interactions that occur pre- and post-transplantation. PB-2 was compared with the conventional standardized Collins-2 flush solution in the preservation of autografts in dogs and was found to provide significantly improved renal recovery, viability, and survival. Studies to test the new solution in human renal allograft transplant preservation are planned.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6021184af869ff2dccfe63b9f7cc91e8 https://doi.org/10.3949/ccjm.58.1.54 Zobrazit plný text záznamu