Differential impact of behavioral, social, and emotional apathy on Parkinson's disease

Autor: Masud Husain, Yuen-Siang Ang, Annika Kienast, Daniel Drew, Olivia Plant, Elitsa Slavkova, Marin Tamm, Patricia L. Lockwood
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Annals of Clinical and Translational Neurology
ISSN: 2328-9503
Popis: Apathy is highly prevalent in Parkinson's disease. New findings suggest the syndrome is multifaceted. Here, we investigate whether all aspects of apathy are equally affected in Parkinson's disease and whether different dimensions of apathy were associated with depression and anhedonia. On the Apathy Motivation Index, while behavioral apathy and social apathy were elevated, emotional motivation was relatively preserved in Parkinson's disease, although a few patients did show impaired emotional sensitivity. Behavioral and social, but not emotional, apathy was associated with depression and anhedonia. These findings suggest aspects of motivation can be selectively impaired in Parkinson's disease and may have implications for guiding treatment.
Databáze: OpenAIRE
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