Retinal abnormalities in Universal Eye Screening of healthy, full-term newborn infant in Jakarta. The incidence and its risk factors: A Pilot study
| Autor: | Julie Dewi Barliana, Rinawati Rohsiswatmo, Indah Suci Widyahening, Dian Estu Yulia, Rita S. Sitorus, Indra Maharddhika Pambudy |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pediatrics
medicine.medical_specialty Univariate analysis Newborn screening business.industry Incidence (epidemiology) medicine.medical_treatment Protective factor Chorioretinitis Hemorrhage Healthy newborn Fundus (eye) RE1-994 medicine.disease Ophthalmology Universal eye screening Medicine Caesarean section Original Article business Delivery Full Term |
| Zdroj: | International Journal of Retina and Vitreous International Journal of Retina and Vitreous, Vol 7, Iss 1, Pp 1-7 (2021) |
| DOI: | 10.21203/rs.2.10617/v2 |
| Popis: | Aim To screen for ocular abnormalities in healthy full-term newborn infants using wide-field digital imaging and to analyze factors associated with the findings. Methods A total of 1208 full-term newborn infants at a tertiary eye hospital (Cipto Mangunkusumo National Referral Hospital) and a district hospital in Jakarta (Koja Hospital) were enrolled to the study. All eligible newborns underwent fundus examination within 48 h after birth using the RetCam shuttle (Natus Medical Incorporated, USA). Retinal findings were documented and analyzed according to obstetric and neonatal risk factors. Results Of the 1208 newborn infants enrolled, ocular abnormalities were found in 150 infants (12.4%). Retinal hemorrhage (RH) was the most common finding (88%) in which 2.67% involved the macula, followed by chorioretinitis (4.67%). Univariate analysis showed caesarean section (C-section) (OR 0.27, 95% CI 0.18–0.41, p Conclusions Our study showed that universal eye screening in healthy neonates is beneficial in the early diagnosis, monitoring and treatment of ocular abnormalities such as retinal hemorrhage, chorioretinitis and retinoblastoma. Retinal hemorrhage is the most common ocular abnormality and is associated with the delivery method and the duration of labor. Universal eye screening is visual-saving and life-saving for neonates with chorioretinitis, retinoblastoma as well as other abnormalities and should be mandatory in newborn screening. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|