Cryotherapy: biochemical alterations involved in reduction of damage induced by exhaustive exercise

Autor: Gustavo Orione Puntel, Andrezza Bond Vieira Furtado, Diane Duarte Hartmann, Rodrigo Pereira Martins, Luis Ulisses Signori, I.K. da Silva, Félix Alexandre Antunes Soares, Bárbara Santos Luccas Duarte, Pâmela Carvalho da Rosa
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Muscular damage
Male
Antioxidant
Time Factors
Physiology
medicine.medical_treatment
Treatment outcome
Tetrazolium Salts
Cryotherapy
Pharmacology
Muscle damage
Biochemistry
Antioxidants
Mice
0302 clinical medicine
Immersion
General Pharmacology
Toxicology and Pharmaceutics
lcsh:QH301-705.5
Research Articles
lcsh:R5-920
Physical conditioning
General Neuroscience
General Medicine
Fluoresceins
Cold Temperature
Treatment Outcome
Acetylcholinesterase
lcsh:Medicine (General)
Cell Survival
Immunology
Analgesic
Biophysics
Ocean Engineering
Exercise-induced damage
03 medical and health sciences
Cold-water immersion
Reactive species
Physical Conditioning
Animal
medicine
Effective treatment
Animals
Viability assay
Muscle
Skeletal
Swimming
Myositis
business.industry
Reproducibility of Results
Water
030229 sport sciences
Cell Biology
Thiazoles
lcsh:Biology (General)
Therapeutic cold
business
Reactive Oxygen Species
030217 neurology & neurosurgery
Zdroj: Brazilian Journal of Medical and Biological Research
Brazilian Journal of Medical and Biological Research v.51 n.11 2018
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Volume: 51, Issue: 11, Article number: e7702, Published: 04 OCT 2018
Brazilian Journal of Medical and Biological Research, Vol 51, Iss 11 (2018)
ISSN: 1414-431X
0100-879X
Popis: When exercises are done in intense or exhaustive modes, several acute biochemical mechanisms are triggered. The use of cryotherapy as cold-water immersion is largely used to accelerate the process of muscular recovery based on its anti-inflammatory and analgesic properties. The present study aimed to study the biochemical effects of cold-water immersion treatment in mice submitted to exercise-induced exhaustion. Swiss albino mice were divided into 4 treatment groups: control, cold-water immersion (CWI), swimming exhaustive protocol (SEP), and SEP+CWI. Treatment groups were subdivided into times of analysis: 0, 1, 3, and 5 days. Exhaustion groups were submitted to one SEP session, and the CWI groups submitted to one immersion session (12 min at 12°C) every 24 h. Reactive species production, inflammatory, cell viability, and antioxidant status were assessed. The SEP+CWI group showed a decrease in inflammatory damage biomarkers, and reactive species production, and presented increased cell viability compared to the SEP group. Furthermore, CWI increased acetylcholinesterase activity in the first two sessions. The present study showed that CWI was an effective treatment after exercise-induced muscle damage. It enhanced anti-inflammatory response, decreased reactive species production, increased cell viability, and promoted redox balance, which could decrease the time for the recovery process.
Databáze: OpenAIRE
Externí odkaz: