The apheresis platelet donation was increased after a nationwide ban on family/replacement donation in China
| Autor: | Ying Li, Liqiao Zhou, Yongshui Fu, Shi-Jie Li, Jin-Yan Chen, Guoli Zhou, Huiyou Chen, Xuemei Fu, Jianxun Kang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Blood Platelets
Male China medicine.medical_specialty Piecewise linear mixed model Plateletpheresis donation Plateletpheresis Blood Donors 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Epidemiology medicine Humans 030212 general & internal medicine Ban on family/replacement donation business.industry Research Public Health Environmental and Occupational Health Pseudo-panel data approach Blood donor Apheresis Donation Cohort Biostatistics Public aspects of medicine RA1-1270 business Linear trend Demography |
| Zdroj: | BMC Public Health BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021) |
| ISSN: | 1471-2458 |
| Popis: | Background A nationwide ban on family/replacement donation (FRD) went into effect on April 1, 2018 in China. To date, no reports relevant to the trend of plateletpheresis donations before and after a nationwide ban on FRD were found. Methods We used two independent full samples, consisting of 135,851 and 82,129 plateletpheresis donors from Guangzhou and Chengdu between October 2012 and September 2019, respectively. A pseudo-panel data approach was applied by grouping three time-invariant covariates – gender, blood donation history, and birth year across 14 cross-sections (a 6-month interval each) to form a total of 24 cohort groups (14 × 24 = 336 cohorts, i.e., cells) with each having common covariates. The outcome was average apheresis platelet units per donor in each cell. We performed a two-piecewise linear mixed model with the cross-section (i.e., time) just right before the ban as a time breakpoint (i.e., 11th cross-section) to examine the trend of outcome with the adjustment of three time-invariant covariates. We removed the FRDs in each of the first 11 cross-sections to detect its possible influence on the trend. Results The final model for the samples from Guangzhou presented a two-piecewise linear trend of the outcome over time with a horizontal line to the left of the breakpoint (βtimeBefore11 = 0.0111, p = 0.0976) and a significantly positive linear trend to the right (βtimeAfter11 = 0.0404, p Conclusion The significant increase of the average apheresis platelet units per donor over time after the FRD ban may be related to the implement of the FRD ban and the improved donation behavior of male donors and/or donors with platelet donation history after the ban. Our findings may potentially motivate the policymakers in other countries where the FRD for plateletpheresis donation is still legitimate to phase out their FRD strategy and ultimately achieve 100% voluntary plateletpheresis donation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink