Epidemiological assessment of continuing transmission of lymphatic filariasis in Samoa
| Autor: | Wayne Melrose, Take Naseri, U Silva, Patrick J. Lammie, Fuatai Maiava, Hayley Joseph |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Recombinant antigen Samoa Antibodies Helminth law.invention Filariasis Young Adult Age Distribution Elephantiasis Filarial Seroepidemiologic Studies law Epidemiology Prevalence Animals Humans Medicine Wuchereria bancrofti Sex Distribution Child Antibody prevalence Lymphatic filariasis Aged Aged 80 and over Blood Specimen Collection biology business.industry Middle Aged medicine.disease Infectious Diseases Transmission (mechanics) Antigens Helminth Child Preschool Immunology biology.protein Female Original Article Parasitology Antibody business Filarial antigen |
| Zdroj: | Annals of Tropical Medicine & Parasitology. 105:567-578 |
| ISSN: | 1364-8594 0003-4983 |
| DOI: | 10.1179/2047773211y.0000000008 |
| Popis: | Ongoing transmission of lymphatic filariasis (LF) was assessed in five Samoan villages by measuring microfilaraemia (Mf), circulating filarial antigen (CFA) and antibody prevalence. Compared to the other villages, Fasitoo-Tai had a significantly higher Mf prevalence (3.2%), CFA prevalence (14.6%) and antibody prevalence in children (62.0%) (P1% CFA prevalence and a high antibody prevalence in children (46.6%). Overall, antibody prevalence in children appeared to reflect the transmission dynamics in the villages and, in Siufaga, identified an area of ongoing transmission. The Filariasis Cellabs Enzyme-Linked Immunosorbent Assay (CELISA), based on recombinant antigen Bm14, to detect antibodies, could potentially be a promising diagnostic tool for inclusion in future surveillance in the South Pacific. |
| Databáze: | OpenAIRE |
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