The marine biodiscovery pipeline and ocean medicines of tomorrow
Autor: | Donatella de Pascale, Adrianna Ianora, Marcel Jaspars, Alexander D. Crawford, Fernando Reyes, Jeannette Hammer Andersen |
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Přispěvatelé: | [Jaspars, Marcel] Univ Aberdeen, Marine Biodiscovery Ctr, Dept Chem, Aberdeen AB24 3UE, Scotland, [De Pascale, Donatella] CNR, Inst Prot Biochem, Via Pietro Castellino 111, I-80131 Naples, Italy, [Andersen, Jeanette H.] Univ Tromso, Forskningspk FPARK A 203, Tromso, Norway, [Reyes, Fernando] Fdn MEDINA, Parque Tecnol Ciencias Salud,Av Conocimiento 34, Granada 18016, Spain, [Crawford, Alexander D.] Univ Leuven, Lab Mol Biodiscovery, Herestr 49, B-3000 Leuven, Belgium, [Ianora, Adrianna] Stn Zool Anton Dohrn, Villa Comunale 80121, Naples, Italy, EU Seventh Framework Programme |
Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
VDP::Agriculture and fishery disciplines: 900::Fisheries science: 920 Engineering Multidisciplinaire généralités & autres [D99] [Sciences de la santé humaine] business.industry Systems Pain ocean medicines PharmaSea project Aquatic Science Pipeline (software) Natural-products drug discovery 03 medical and health sciences 030104 developmental biology Oceanography 14. Life underwater Biochemical engineering business VDP::Landbruks- og Fiskerifag: 900::Fiskerifag: 920 Multidisciplinary general & others [D99] [Human health sciences] |
Zdroj: | Journal of the Marine Biological Association of the United Kingdom, 96(01), 151-158. New York, NY: Cambridge University Press (2016). |
Popis: | Marine organisms possess the capacity to produce a variety of unique and biologically potent natural products for treating human diseases, many of which are currently commercially available or are in advanced clinical trials. Here we provide a short review on progress in the field and discuss a case study of an EU-funded project, PharmaSea, which aims to discover novel products for the treatment of infections, inflammation and neurodegenerative diseases. Research in this sector is opening new doors for harnessing the potential of marine natural products with pharmaceutical properties. |
Databáze: | OpenAIRE |
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