Effects of Neuromuscular Electrical Stimulation on the Masticatory Muscles and Physiologic Sleep Variables in Adults with Cerebral Palsy: A Novel Therapeutic Approach

Autor: Eduardo Grossmann, Lilian Chrystiane Giannasi, Luis Vicente Franco de Oliveira, Sandra Regina Batista Freitas, Israel Reis Santos, Bruna F. Caldas, Miriam Yumi Matsui, José Benedito Oliveira Amorim, Claudia Santos Oliveira, Mônica Fernandes Gomes
Přispěvatelé: Universidade Estadual Paulista (Unesp), Anatomy Laboratory, Federal University of Rio Grande do Sul- UFRGS, Porto Alegre, RS, Brazil., Rehabilitation Sciences Master and PhD Program, Nove de Julho University-UNINOVE, São Paulo, Brazil.
Rok vydání: 2015
Předmět:
Zdroj: PLoS ONE, Vol 10, Iss 8, p e0128959 (2015)
PubMed
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
PLoS ONE
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0128959
Popis: Made available in DSpace on 2015-12-07T15:35:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2015. Added 1 bitstream(s) on 2015-12-07T15:54:20Z : No. of bitstreams: 1 PMC4527754.pdf: 514261 bytes, checksum: 41616c13add0fb550773a5b5c6b5603b (MD5) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Cerebral palsy (CP) is a term employed to define a group of non-progressive neuromotor disorders caused by damage to the immature or developing brain, with consequent limitations regarding movement and posture. CP may impair orapharygeal muscle tone, leading to a compromised chewing function and to sleep disorders (such as obstructive sleep apnea). Thirteen adults with CP underwent bilateral masseter and temporalis neuromuscular electrical stimulation (NMES) therapy. The effects on the masticatory muscles and sleep variables were evaluated using electromyography (EMG) and polysomnography (PSG), respectively, prior and after 2 months of NMES. EMG consisted of 3 tests in different positions: rest, mouth opening and maximum clenching effort (MCE). EMG values in the rest position were 100% higher than values recorded prior to therapy for all muscles analyzed (p < 0.05); mean mouth opening increased from 38.0 ± 8.0 to 44.0 ± 10.0 cm (p = 0.03). A significant difference in MCE was found only for the right masseter. PSG revealed an improved in the AHI from 7.2±7.0/h to 2.3±1.5/h (p < 0.05); total sleep time improved from 185 min to 250 min (p = 0.04) and minimun SaO2 improved from 83.6 ± 3.0 to 86.4 ± 4.0 (p = 0.04). NMES performed over a two-month period led to improvements in the electrical activity of the masticatory muscles at rest, mouth opening, isometric contraction and sleep variables, including the elimination of obstructive sleep apnea events in patients with CP. Trial registration: ReBEC RBR994XFS http://www.ensaiosclinicos.gov.br. Bioscience, State of São Paulo University Julio de Mesquita Filho, UNESP/SJC, São José dos Campos, Brazil; Rehabilitation Sciences Master and PhD Program, Nove de Julho University-UNINOVE, São Paulo, Brazil. Bioscience, State of São Paulo University Julio de Mesquita Filho, UNESP/SJC, São José dos Campos, Brazil. Anatomy Laboratory, Federal University of Rio Grande do Sul- UFRGS, Porto Alegre, RS, Brazil. Rehabilitation Sciences Master and PhD Program, Nove de Julho University-UNINOVE, São Paulo, Brazil. Bioscience, State of São Paulo University Julio de Mesquita Filho, UNESP/SJC, São José dos Campos, Brazil; Rehabilitation Sciences Master and PhD Program, Nove de Julho University-UNINOVE, São Paulo, Brazil. Bioscience, State of São Paulo University Julio de Mesquita Filho, UNESP/SJC, São José dos Campos, Brazil. CAPES: 02495/09-0
Databáze: OpenAIRE
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