Alterations of cross-bridge kinetics in human atrial and ventricular myocardium

Autor:	Thorsten Ruf, Jens Lüdemann, Hanjörg Just, Friedhelm Beyersdorf, H. Posival, Christian Holubarsch, Heiner Schulte-Baukloh
Rok vydání:	1999
Předmět:	Cardiomyopathy Dilated medicine.medical_specialty Heart disease Physiology Myosin ATPase Heart Ventricles Barium Compounds Cardiomyopathy Stimulation In Vitro Techniques Body Temperature Contractility Chlorides Physiology (medical) Isoprenaline Internal medicine medicine Humans Heart Atria Atrium (architecture) Chemistry Isoproterenol Heart Actomyosin Adrenergic beta-Agonists medicine.disease Elasticity Stimulation Chemical Cardiology Contracture medicine.symptom Cardiology and Cardiovascular Medicine medicine.drug
Zdroj:	Cardiovascular research. 40(3)
ISSN:	0008-6363
Popis:	Condensed abstract: We analyzed actomyosin cross-bridge kinetics in human atrial and ventricular muscle strip preparations by using sinusoidal length changes from 0.1 to 60 Hz. The minimum stiffness frequency was higher in atrial than in ventricular human myocardium and lower in failing than in non-failing left ventricular human myocardium. β-Adrenergic stimulation increased the minimum stiffness frequency by 18±3% ( p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6006e33d5d233875121a47d324b315ef https://pubmed.ncbi.nlm.nih.gov/10070500 Zobrazit plný text záznamu