Multifaceted Strategy for the Synthesis of Diverse 2,2'-Bithiophene Derivatives
| Autor: | Grażyna Szafraniec-Gorol, Agnieszka Iwan, Ewa Schab-Balcerzak, Jan Grzegorz Małecki, Mateusz Penkala, Michal Filapek, Slawomir Kula, Stanisław Krompiec, Agata Szlapa, Witold Danikiewicz, Joanna Malarz, Dariusz Blach, Michal Pajak, Iwona Grudzka-Flak, Aneta Slodek, Marek Matussek, M. Mierzwa, Beata Marcol, Marian Paluch, Bartosz Boharewicz |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Allylic rearrangement
Double bond bithiophene derivatives Pharmaceutical Science Homogeneous catalysis Thiophenes Catalysis Article isomerization Analytical Chemistry lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry Drug Discovery Organic chemistry Physical and Theoretical Chemistry Isoxazole coupling cycloaddition Pyrrole Amination chemistry.chemical_classification Cycloaddition Reaction Molecular Structure Organic Chemistry Combinatorial chemistry homogeneous catalysis Cycloaddition high pressure PTC chemistry Acetylene Chemistry (miscellaneous) Molecular Medicine Isomerization |
| Zdroj: | Molecules, Vol 20, Iss 3, Pp 4565-4593 (2015) Molecules Volume 20 Issue 3 Pages 4565-4593 |
| ISSN: | 1420-3049 |
| Popis: | New catalytically or high pressure activated reactions and routes, including coupling, double bond migration in allylic systems, and various types of cycloaddition and dihydroamination have been used for the synthesis of novel bithiophene derivatives. Thanks to the abovementioned reactions and routes combined with non-catalytic ones, new acetylene, butadiyne, isoxazole, 1,2,3-triazole, pyrrole, benzene, and fluoranthene derivatives with one, two or six bithiophenyl moieties have been obtained. Basic sources of crucial substrates which include bithiophene motif for catalytic reactions were 2,2'-bithiophene, gaseous acetylene and 1,3-butadiyne. |
| Databáze: | OpenAIRE |
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