Homomorphic Adenocarcinoma Metastases to the Liver: A Report of 2 Cases
| Autor: | Payman Fathizadeh, Simcha Weissman, Rani Berry, Melanie Burgos, Tej I Mehta, James H. Tabibian, Alex Zhornitskiy |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Ampulla of Vater Adenocarcinoma Malignancy Rare Diseases Medicine Humans Endoscopy Digestive System Neoplasm Metastasis Ampulla Cancer medicine.diagnostic_test business.industry Liver Disease Liver Neoplasms General Medicine Articles medicine.disease Primary tumor Immunohistochemistry Endoscopy medicine.anatomical_structure Etiology Digestive Diseases business |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| Popis: | Case series Patients: Male, 51-year-old • Male, 46-year-old Final Diagnosis: Metastatic hepatic malignancy Symptoms: Weight loss Medication: — Clinical Procedure: Endoscopy Specialty: Gastroenterology and Hepatology Objective: Rare disease Background: Distinguishing between primary and metastatic malignancy can be challenging despite advances in diagnostic imaging, tissue sampling techniques, and immunohistochemistry. Case Reports: Herein, we describe 2 cases of obscure liver lesions which were ultimately determined to be malignant and from metastatic disease. In both cases, the liver metastases were uniquely “homomorphic,” i.e., radiographically resembling the primary tumor source (in the first case a dilated tubular appearance akin to the hepatopancreatic ampulla and in the second case a haustrated bowel appearance akin to the colon). Conclusions: These cases illustrate the recently reported concept of tumor homomorphism as a potential diagnostic pearl to facilitate timely diagnosis of malignant-appearing liver lesions of obscure etiology and source and thereby guide management accordingly. |
| Databáze: | OpenAIRE |
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