Differentiation of histopathological growth patterns of colorectal liver metastases by MRI features
| Autor: | Yi Liu, Shuai Wang, Wen-Hui Li, Xin-Fang Wang, Rui-Mei Chai, Yong-Feng Wang |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Quant Imaging Med Surg |
| ISSN: | 2223-4306 2223-4292 |
| DOI: | 10.21037/qims-21-143 |
| Popis: | BACKGROUND: It is necessary to develop an accurate non-invasive method to determine the histopathological growth pattern (HGP) of colorectal liver metastasis (CRLM) before surgery. The present study aimed to identify various HGPs of CRLM by magnetic resonance imaging (MRI) features. METHODS: This retrospective study included 53 chemo-naïve patients with CRLM between December 2013 and September 2019. The HGPs of CRLM were assessed according to the international consensus guidelines, and were classified as either replacement HGP (rHGP) or non-rHGP. The MRI features of CRLM were retrospectively reviewed in consensus by two radiologists. The differences of MRI features between rHGP and non-rHGP tumors were compared by using Chi-square test and Student’s t-test. The Spearman or Pearson correlation analysis was performed to determine the correlation between different MRI features. A receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic ability. RESULTS: Of the 53 chemo-naïve patients (mean age, 60.11±9.85 years; age range, 38–86 years), 12 were diagnosed as rHGP, while 41 were diagnosed as non-rHGP. Rim enhancement were more common in rHGP than in non-rHGP (P |
| Databáze: | OpenAIRE |
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