Supplementary Figures S1-S14 from Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis

Autor: Antonio García de Herreros, Cristina Peña, Josep Baulida, J. Ignacio Casal, Félix Bonilla, Mercedes Herrera, Raúl Peña, Aida Mestre-Farrera, Rubén Olivera-Salguero, Lorena Alba-Castellón
Rok vydání: 2023
DOI: 10.1158/0008-5472.22412768
Popis: Invasion of colon and breast cancer cell lines (S1); Mesenchymal Stem Cells enhance tumor invasion through Collagen or Matrigel matrices (S2); Invasion of HT-29 M6 is preceded by that of MSCs (S3); Generation of MSCs and MEFs depleted in Snail1 (S4); Generation of HT-29 M6 Snail1 CRISPR KO cells (S5); Genes differently regulated by HT-29 M6 in MSCs wild-type and Snail1 KO (S6); Prostaglandin E2 acts as a chemoattractant (S7); Inhibition of PGE2 signaling prevents HT-29 M6 invasion (S8); PGE2 stimulates HT-29 M6 invasion (S9); Snail1 expression in MSCs is required for the MSCs stimulation of invasion of different epithelial cell lines (S10); Expression of EP4 PGE2 receptor in epithelial cell lines (S11); Isolation of murine and human CAFs with different Snail1 levels (S12); Identification of ePyMT metastases in the lung (S13); Celecoxib does not modify tumor size in ePyMT-MSCs co-xenografts (S14).
Databáze: OpenAIRE