Clinical profile and outcome of familial versus non-familial atrial fibrillation
| Autor: | Hooman Bakhshandeh, Amirfarjam Fazelifar, Mona Heidarali, Majid Haghjoo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Population Cardiomyopathy Catheter ablation Iran 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine Cardiac interventions Atrial Fibrillation medicine Humans 030212 general & internal medicine education education.field_of_study business.industry Medical record Atrial fibrillation Middle Aged medicine.disease Treatment Outcome Concomitant Catheter Ablation Female Cardiomyopathies Cardiology and Cardiovascular Medicine business Familial atrial fibrillation |
| Zdroj: | International Journal of Cardiology. 314:70-74 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2020.03.080 |
| Popis: | There is paucity of information on clinical characteristics and outcome of patients with familial atrial fibrillation (AF). The present study was aimed to compare clinical profile and outcome of familial AF with those of non-familial AF.Between February 2017 and February 2018, we enrolled 738 participants (60% men, median age, 51 years in familial AF vs. 61 years in non-familial AF) from Iranian Registry of AF. All patients were followed for 12 months. Clinical characteristics and main outcome measures for AF patients were obtained from patient's medical records.A positive history of AF in first-degree relative was reported in 15.3% of our AF population. Familial AF group were significantly younger than non-familial group (p = 0.001). Concomitant sinus node dysfunction and cardiomyopathies were more common in familial AF group (p = 0.02, p = 0.004, respectively). Patients with familial AF were also likely to receive cardiac devices and AF catheter ablation (all p 0.05). However, all-cause mortality and thromboembolic events were similar (all p 0.05).Familial AF patients were more likely to have associated rhythm disorders and dilated cardiomyopathies. Cardiac interventions were also more common in familial patients. However, they did not differ significantly in their long-term outcome. |
| Databáze: | OpenAIRE |
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