Development of sexual structures influences metabolomic and transcriptomic profiles in Aspergillus flavus

Autor: Jane Marian Luis, Ignazio Carbone, Brian M. Mack, Matthew D. Lebar, Jeffrey W. Cary, Matthew K. Gilbert, Deepak Bhatnagar, Carol-Carter Wientjes, Gary A. Payne, Geromy G. Moore, Yaken Obaydeh Ameen, Peter S. Ojiambo
Rok vydání: 2022
Předmět:
Zdroj: Fungal Biology. 126:187-200
ISSN: 1878-6146
DOI: 10.1016/j.funbio.2022.01.001
Popis: Sclerotium (female) fertility, the ability of a strain to produce ascocarps, influences internal morphological changes during sexual reproduction in Aspergillus flavus. Although sclerotial morphogenesis has been linked to secondary metabolite (SM) biosynthesis, metabolic and transcriptomic changes within A. flavus sclerotia during sexual development are not known. Successful mating between compatible strains may result in relatively high or low numbers of ascocarps being produced. Sclerotia from a high fertility cross (Hi-Fert-Mated), a low fertility cross (Lo-Fert-Mated), unmated strains (Hi-Fert-Unmated and Lo-Fert-Unmated) were harvested immediately after crosses were made and every two weeks until 8 weeks of incubation, then subjected to targeted metabolomics (n = 106) and transcriptomics analyses (n = 80). Aflatoxin B
Databáze: OpenAIRE