Association Between Rectus Abdominis Denervation and Ventilation Dysfunction in Patients with Amyotrophic Lateral Sclerosis
| Autor: | Ying-sheng Xu, Nan Zhang, Shuo Zhang, Huagang Zhang, Dongsheng Fan |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Vital capacity medicine.medical_specialty Paraspinal Muscles Rectus Abdominis lcsh:Medicine Action Potentials Electromyography Quadriceps Muscle 03 medical and health sciences FEV1/FVC ratio Young Adult 0302 clinical medicine medicine Humans Respiratory function Ventilation Dysfunction Amyotrophic lateral sclerosis Aged Denervation Aged 80 and over Motor Neurons medicine.diagnostic_test business.industry lcsh:R Amyotrophic Lateral Sclerosis General Medicine Middle Aged medicine.disease Dyspnea Forced Vital Capacity Diaphragm (structural system) Surgery respiratory tract diseases Electrophysiology 030228 respiratory system Anesthesia Breathing Female Original Article business 030217 neurology & neurosurgery |
| Zdroj: | Chinese Medical Journal Chinese Medical Journal, Vol 129, Iss 17, Pp 2063-2066 (2016) |
| ISSN: | 2542-5641 |
| Popis: | Background: Spontaneous potentials in electromyography (EMG) of paraspinal muscles are associated with diaphragm denervation and, therefore, poor respiratory function in amyotrophic lateral sclerosis (ALS) is understandable. EMG changes in the rectus abdominis (RA) display an effect similar to those in paraspinal muscles with respect to the function of lower motor neurons in the thoracic spinal cord. The RA denervation was examined to determine its association with ventilation dysfunction in ALS. Methods: We collected the clinical data of 128 patients with sporadic ALS in Department of Neurology of Peking University Third Hospital from 2009 to 2013. EMG, Revised ALS Functional Rating Scale (ALSFRS-R) and forced vital capacity (FVC) were performed in all patients and the differences in the EMG changes in RA between those with and without FVC ≥ 80% were analysed. Results: The mean FVC value was 83.4% ± 17.1% (range: 45%–131%) of the predicted value. A total of 79 patients displayed FVC ≥80%, and 49 patients displayed FVC |
| Databáze: | OpenAIRE |
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