Role of neutrophil-lymphocyte ratio as a predictive factor of glioma tumor grade: A systematic review
| Autor: | Alexandra Gomes Dos Santos, Tamires Martins Silva, Artur Nóbrega Lima Rodrigues de Morais, Rodolfo Figueiredo de Carvalho, Adilson Jose Manuel de Oliveira, Victor Matheus Ribeiro Baylão, Mayara Azevedo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Oncology medicine.medical_specialty Neutrophils Lymphocyte 03 medical and health sciences Tumor grade 0302 clinical medicine Internal medicine Glioma medicine Humans Lymphocytes Neutrophil to lymphocyte ratio Primary Brain Tumors Grading (tumors) business.industry Brain Neoplasms fungi Hematology medicine.disease Prognosis Predictive factor 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Differential diagnosis business |
| Zdroj: | Critical reviews in oncology/hematology. 163 |
| ISSN: | 1879-0461 |
| Popis: | Gliomas are the main type of intra-axial primary brain tumors. We performed a systematic review of studies on the neutrophil-to-lymphocyte ratio (NLR) and its role in the prognosis of patients with gliomas. An English-language literature-based search, using the PubMed and Biblioteca Virtual em Saude databases, was conducted for papers published until May 2, 2020. The quality of the selected articles was stratified using the Newcastle-Ottawa scale's criteria. We found 137 publications for a query string. After applying the inclusion criteria, 13 articles were selected. Seven studies assessed overall survival and found high NLR values associated with poor overall survival. Six studies approached the issue of tumor grading and differential diagnosis and demonstrated that patients with high NLR values were diagnosed with high-grade gliomas. NLR is a low-cost method and an effective prognostic factor associated with tumor grading and OS in patients with gliomas. |
| Databáze: | OpenAIRE |
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