Red light-triggered photoreduction on a nucleic acid template

Autor: Andriy Mokhir, Patrick Duchstein, Jennifer Rühle, Dirk Zahn, Margot Schikora, Nina S. Deussner-Helfmann, Mike Heilemann, Subrata Dutta, Timofei S. Zatsepin, Günther Knör
Rok vydání: 2020
Předmět:
Zdroj: Chemical communications (Cambridge, England). 56(69)
ISSN: 1364-548X
Popis: Conjugate Sn(IV)(pyropheophorbide a)dichloride–(peptide nucleic acid) catalyzes reduction of azobenzene derivatives in the presence of complementary nucleic acid (NA) upon irridiation with red light (660 nm). This is the first red light-induced NA-templated photoreduction. It is highly sensitive to single mismatches in the NA-template and can detect down to 5 nM NAs.
Databáze: OpenAIRE