A pragmatic approach to infants with Robin sequence: a retrospective cohort study and presence of a treatment algorithm
| Autor: | Bram Smarius, Titia L. E. M. Niers, Emma C. Paes, Esther S. Veldhoen, Aebele B. Mink van der Molen, Marvick S. M. Muradin, Moshe Kon, Daan P. F. van Nunen, Corstiaan C. Breugem, Lucienne Speleman |
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| Přispěvatelé: | Amsterdam Reproduction & Development (AR&D) |
| Jazyk: | angličtina |
| Předmět: |
Robin Sequence
Pediatrics medicine.medical_specialty Approach business.industry Critically ill Dentistry(all) Pierre Robin Retrospective cohort study Mandibular distraction Multidisciplinary team Treatment Tongue lip adhesion Journal Article Medicine Original Article Decision process Tracheotomy business General Dentistry Tongue–lip adhesion |
| Zdroj: | Clinical Oral Investigations Clinical oral investigations, 19(8), 2101-2114. Springer Verlag Clinical Oral Investigations, 19(8), 2101. Springer Verlag |
| ISSN: | 1432-6981 |
| DOI: | 10.1007/s00784-015-1407-6 |
| Popis: | Objectives: Initial approaches to and treatments of infants with Robin sequence (RS) is diverse and inconsistent. The care of these sometimes critically ill infants involves many different medical specialties, which can make the decision process complex and difficult. To optimize the care of infants with RS, we present our institution’s approach and a review of the current literature. Material and methods: A retrospective cohort study was conducted among 75 infants diagnosed with RS and managed at our institution in the 1996–2012 period. Additionally, the conducted treatment regimen in this paper was discussed with recent literature describing the approach of infants with RS. Results: Forty-four infants (59 %) were found to have been treated conservatively. A significant larger proportion of nonisolated RS infants than isolated RS infants needed surgical intervention (53 vs. 25 %, p =.014). A mandibular distraction was conducted in 24 % (n = 18) of cases, a tracheotomy in 9 % (n = 7), and a tongue–lip adhesion in 8 % (n = 6). Seventy-seven percent of all infants had received temporary nasogastric tube feeding. The literature review of 31 studies showed that initial examinations and the indications to perform a surgical intervention varied and were often not clearly described. Conclusions: RS is a heterogenic group with a wide spectrum of associated anomalies. As a result, the decisional process is challenging, and a multidisciplinary approach to treatment is desirable. Current treatment options in literature vary, and a more uniform approach is recommended. Clinical Relevance: We provide a comprehensive and pragmatic approach to the analysis and treatment of infants with RS, which could serve as useful guidance in other clinics. |
| Databáze: | OpenAIRE |
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