Simultaneous determination of deuterium-labeled ergosterol and brassicasterol in stroke-prone spontaneously hypertensive rats by ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometry

Autor:	Koichi Machida, Yuji Koseki, Akira Kotani, Kazuhiro Yamamoto, Tsuyoshi Miura, Hideki Hakamata
Rok vydání:	2022
Předmět:	Stroke Spectrometry Mass Electrospray Ionization Tandem Mass Spectrometry Ergosterol Rats Inbred SHR General Chemical Engineering General Engineering Animals Deuterium Chromatography High Pressure Liquid Rats Analytical Chemistry
Zdroj:	Analytical Methods. 14:4879-4885
ISSN:	1759-9679 1759-9660
Popis:	A highly sensitive LC-MS/MS method disclosed that deuterium-labeled brassicasterol in serum was increased in a time-dependent manner, when deuterium-labeled ergosterol was orally administrated to stroke-prone spontaneously hypertensive rats.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd9f54b62f7ade428f0598a4ae57c9a https://doi.org/10.1039/d2ay01705a Zobrazit plný text záznamu