CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA

Autor: Ching-Chun Yang, Chih-Hsu Chang, Heng-Li Chen, Ming-Chieh Chou, Ching-Jen Yang, Ren-Shiang Jhou, Er-Yi Huang, Hung-Cheng Li, Ching-Shu Suen, Ming-Jing Hwang, Chiaho Shih
Rok vydání: 2018
Předmět:
Zdroj: Cell reports. 38(10)
ISSN: 2211-1247
Popis: Hepatitis B virus (HBV) is a global pathogen. We report here that the cellular CRM1 machinery can mediate nuclear export of entire HBV core (HBc) particles containing encapsidated viral RNAs. Two CRM1-mediated nuclear export signals (NES
Databáze: OpenAIRE