Allergenic interrelationship of epidermis, blood serum, and skeletal muscle

Autor: Frank A. Simon
Rok vydání: 2010
Předmět:
Zdroj: The Journal of allergy. 17
ISSN: 0021-8707
Popis: 1.1. Direct skin tests and local passive transfer studies were carried out on ten selected patients with extracts of epidermis, serum, and skeletal muscle of the dog, horse, cow, hog, guinea pig, and man. Various combinations of positive reactions were found, varying from positive tests to all three tissues of all six species excepting man to organ-specific and species-specific reactions to a single substance. 2.2. Antibody neutralization studies indicated that: (a) in four cases dog epidermis could have been the only sensitizing allergen; (b) in two cases dog epidermis, dog serum, or dog muscle could have been the only sensitizing allergen; (c) in one case horse serum could have been the only sensitizing allergen; (d) in one case there was species-specific hypersensitiveness to both dog epidermis and to human epidermis; (e) in one case there was species-specific hypersensitiveness to both dog epidermis and to horse epidermis. In one case horse epidermis alone reacted positively.
Databáze: OpenAIRE