Effect of prostaglandin E2 on the permeability of the iris vessels to horseradish peroxidase in the rabbit
| Autor: | Trombitás K, I. Takáts, E. Pintér, A. Tigyi-Sebes |
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| Rok vydání: | 1978 |
| Předmět: |
Male
medicine.medical_specialty Iris Horseradish peroxidase law.invention Capillary Permeability Cellular and Molecular Neuroscience law Internal medicine medicine Animals Iris (anatomy) Prostaglandin E2 Horseradish Peroxidase biology Chemistry Prostaglandins E Rabbit (nuclear engineering) Sensory Systems Ophthalmology medicine.anatomical_structure Endocrinology Permeability (electromagnetism) biology.protein Biophysics Female Rabbits Electron microscope Intracellular Peroxidase medicine.drug |
| Zdroj: | Albrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie. 207:221-228 |
| ISSN: | 1435-702X 0065-6100 |
| DOI: | 10.1007/bf00411056 |
| Popis: | Prostaglandin E2 (0.5 microgram in 10 microliter 10% ethanol) was introduced into the anterior chambers of rabbit eyes. Using the horseradish peroxidase method, it was shown under the electron microscope that the endothelial barrier of the iris vessels broke down. The peroxidase penetrated as far as the basis of the posterior epithelial cells, however, without entering their lateral intercellular spaces. The question of whether the effect of prostaglandins on the barrier was a direct effect or at least a partially indirect one, i.e., a haemodynamic action, is discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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