The long-term efficacy of cryoballoon vs irrigated radiofrequency ablation for the treatment of atrial fibrillation: A meta-analysis
| Autor: | Lin qiong Liu, Zengzhang Liu, Xiaocheng Cheng, Tong Chen, Changyue Zhou, Xuewen Tang, Qiongwen Hu |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Radiofrequency ablation MEDLINE Atrial fibrillation Cochrane Library medicine.disease Cryosurgery Pulmonary vein Surgery law.invention Treatment Outcome Randomized controlled trial law Meta-analysis Internal medicine Relative risk Atrial Fibrillation Catheter Ablation Cardiology medicine Humans Cardiology and Cardiovascular Medicine business Randomized Controlled Trials as Topic |
| Zdroj: | International Journal of Cardiology. 181:297-302 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2014.12.002 |
| Popis: | The main purpose of this meta-analysis was to compare the long-term efficacy of cryoballoon ablation (CBA) with irrigated radiofrequency catheter ablation (RFCA) for the treatment of atrial fibrillation (AF).The Medline, Cochrane Library and Embase Database were searched for clinical studies published up to October 2014. Studies that fulfilled our predefined inclusion criteria were included. The primary clinical outcome was the proportion of patients free from AF (follow-up≥3months), and the secondary clinical outcomes included acute pulmonary vein (PV) isolated rate, fluoroscopy time, procedure time and complications.After a literature search in the major databases, three randomized controlled trials (RCTs) and eight retrospective trials with a total of 1216 patients were identified. Pool-analysis demonstrated that, as compared RFCA, CBA was associated with a similar proportion of patients free from AF at a mean 16.5months follow-up (66.9% vs 65.1%; relative risk [RR]: 1.01; 95% CI: 0.94 to 1.07, P=0.87). Acute PV isolation rate (RR: 0.92; 95% CI: 0.82 to 1.03) and fluoroscopy time (weighted mean difference WMD: -8.60; 95% CI: -18.29 to 3.69) were not statistically significant difference. The procedure time was shorter in CBA group ([WMD]: -31.94; 95% CI: -60.43 to -3.45). Transient phrenic nerve palsy was uniquely observed in the CBA group (5.4%, P0.00001) and resolved in all during the follow-up period, total complication was similar in both groups (RR: 1.30; 95% CI: 0.91 to 1.85).CBA was as effective as RFCA for the treatment of atrial fibrillation during long-term follow-up with comparable procedural features. |
| Databáze: | OpenAIRE |
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