The longevity of antibody to Rickettsia tsutsugamushi in patients with confirmed scrub typhus
| Autor: | A. Shirai, Huxsoll Dl, Saunders Jp, G.W. Brown |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Time Factors Orientia tsutsugamushi Attack rate Prevalence Scrub typhus Serology Humans Medicine Direct fluorescent antibody biology business.industry Malaysia Public Health Environmental and Occupational Health General Medicine bacterial infections and mycoses medicine.disease biology.organism_classification Antibodies Bacterial Virology Infectious Diseases Rickettsia Scrub Typhus Immunology biology.protein Parasitology Antibody business |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 74:253-257 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/0035-9203(80)90254-0 |
| Popis: | Serological surveillance for up to two years of 114 patients with laboratory confirmed scrub typhus showed that antibody to Rickettsia tsutsugamushi as demonstrated by the indirect fluorescent antibody test is short-lived. The mean reversion time from mean peak titre (1:499) was 48.9 weeks and the calculated annual reversion rate to a titre less than 1:50 was 61%. This can be used to estimate attack rates based on point prevalence of antibody. The relationship between antibody prevalence and attack rates observed by other workers was confirmed using this model. The possible uses of the finding and its implications in Malaysia are briefly discussed. |
| Databáze: | OpenAIRE |
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