Italian expert-based recommendations on the use of photo(chemo)therapy in the management of mycosis fungoides: Results of an e-Delphi consensus
| Autor: | Karl P. Lawrence, Piergiacomo Calzavara-Pinton, Emanuele Cozzani, Paolo D. Pigatto, Roberta Piccinno, Emanuele Trovato, Antonello Baldo, Martina Burlando, Maria Concetta Fargnoli, Valeria Brazzelli, Giuseppe Monfrecola, Nicola Pimpinelli, Serena Rupoli, Elisa Molinelli, Vieri Grandi, Carlo Cota, Michele Pellegrino, Paola Savoia, Alberico Motolese, Marco Simonacci, Paolo Iacovelli, Silvia Alberti-Violetti, Emilio Berti, Daniele Gambini, Mauro Alaibac, Aurora Parodi, Marina Venturini, Alessia Pacifico, Pietro Quaglino, Caterina Longo, Giorgio Mozzicafreddo, Pier Luigi Bruni, Paolo Amerio, Alessandro Pileri, Annamaria Offidani |
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| Přispěvatelé: | Grandi V., Baldo A., Berti E., Quaglino P., Rupoli S., Alaibac M., Alberti-Violetti S., Amerio P., Brazzelli V., Bruni P.L., Calzavara-Pinton P., Parodi A., Cozzani E., Burlando M., Fargnoli M.C., Gambini D., Iacovelli P., Pacifico A., Longo C., Monfrecola G., Motolese A., Mozzicafreddo G., Cota C., Pigatto P., Pileri A., Savoia P., Simonacci M., Venturini M., Offidani A., Molinelli E., Pellegrino M., Trovato E., Piccinno R., Lawrence K., Pimpinelli N. |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
mycosis fungoide
medicine.medical_specialty Consensus Skin Neoplasms Delphi Technique Immunology Delphi method Dermatology delphi study evidence-based medicine guideline mycosis fungoides phototherapy 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Mycosis Fungoides Cronbach's alpha medicine Immunology and Allergy Humans Radiology Nuclear Medicine and imaging Medical physics PUVA Therapy computer.programming_language Mycosis fungoides business.industry Advanced stage General Medicine Evidence-based medicine Guideline medicine.disease 030220 oncology & carcinogenesis Chemo therapy business computer Delphi |
| Popis: | Background Phototherapy is a mainstay for the treatment of MF. However, there is scarce evidence for its use, mostly due to the lack of a unified schedule. Aims The primary aim of this study was to establish the first structured, expert-based consensus regarding the indications and technical schedules of NB-UVB and PUVA for MF. The secondary aim was to determine the consensus level for each specific item. Materials & methods E-delphi study. Item-specific expert consensus was defined as the number of "Totally Agree" results to ≥80% of the panelists. Cronbach alpha index ≥0.7 was used as a measure of homogeneity in the responses among questions related to the same topic. Results Overall, there was a high homogeneity among responders (0.78). On specific topics, the highest grade was observed for technical items (0.8) followed by indications for early (0.73) and advanced stages (0.7). Conclusions Items related to the most canonical indications of phototherapy and to treatment schedules showed the highest agreements rates. There is consensus about the use of standardized treatment schedules for the induction and consolidation phases for NB-UVB and PUVA in MF. |
| Databáze: | OpenAIRE |
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