Development of a titanium dioxide-assisted preconcentration/on-site vapor-generation chip hyphenated with inductively coupled plasma-mass spectrometry for online determination of mercuric ions in urine samples
| Autor: | Pei-Chun Chao, Yu-Ting Luo, Yuh-Chang Sun, Yi-An Su, Cheng-Hsing Lin, Jian-Yi Chen, Tsung-Ting Shih, Yi-Hung Liu |
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| Rok vydání: | 2018 |
| Předmět: |
Sorbent
02 engineering and technology Mass spectrometry 01 natural sciences Biochemistry Chloride Mass Spectrometry Analytical Chemistry chemistry.chemical_compound Sodium borohydride medicine Environmental Chemistry Humans Inductively coupled plasma mass spectrometry Spectroscopy Detection limit Ions Titanium Chromatography 010401 analytical chemistry Mercury 021001 nanoscience & nanotechnology 0104 chemical sciences Certified reference materials chemistry Titanium dioxide Volatilization 0210 nano-technology medicine.drug |
| Zdroj: | Analytica chimica acta. 1063 |
| ISSN: | 1873-4324 |
| Popis: | In this study, a novel automatic analytical methodology using a titanium dioxide (TiO2)-assisted preconcentration/on-site vapor-generation (VG) chip hyphenated with inductively coupled plasma-mass spectrometry (ICP-MS) for online determination of mercuric ions (Hg2+) was developed. Interestingly, the TiO2 nanoparticle (nano-TiO2) coating on the channel surface acted not only as a sorbent for preconcentration but also as a catalyst for photocatalyst-assisted VG. Under optimum operation conditions, the developed method was validated by analyzing the certified reference material (CRM) Seronorm™ Trace Elements Urine L-2 (freeze-dried human urine). Based on the obtained results, the dramatic reduction of “hands-on” manipulation and the elimination of hazardous materials (e.g., sodium borohydride (NaBH4) and stannous chloride (SnCl2)) from the process enabled a simple and ultraclean procedure with an extremely low detection limit of 0.75 ng L−1 for Hg2+ in urine samples. To the best of our knowledge, this is the first study to report the direct exploitation of a nano-TiO2-coated microfluidic device for online sample preconcentration and on-site VG prior to ICP-MS measurement. |
| Databáze: | OpenAIRE |
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