Patients with irritable bowel syndrome and constipation are more depressed than patients with functional constipation
| Autor: | Michel Bouchoucha, Cyriaque Bon, Maria Hejnar, Ghislain Devroede, Marouane Boubaya, Robert Benamouzig |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Constipation Gastrointestinal Diseases Anxiety Severity of Illness Index Gastroenterology Irritable Bowel Syndrome Therapeutic approach Surveys and Questionnaires Internal medicine medicine Humans Irritable bowel syndrome Depression (differential diagnoses) Aged Pain Measurement Retrospective Studies Hepatology Depression business.industry Anorectal manometry Middle Aged medicine.disease Abdominal Pain Multivariate Analysis Linear Models Functional constipation Female medicine.symptom business Psychosocial |
| Zdroj: | Digestive and Liver Disease. 46:213-218 |
| ISSN: | 1590-8658 |
| Popis: | Psychosocial factors, such as depression, have been shown to be associated with gastrointestinal disorders like constipation.We retrospectively compared the depression and anxiety profiles of patients with irritable bowel syndrome with constipation versus those of patients with functional constipation using validated questionnaires. Subjects rated the intensity of digestive symptoms experienced during the previous month using visual analogue scales. Colonic transit time measurements and anorectal manometry were performed.Of the 128 consecutive, constipated patients included (84% females, mean age 49.7 ± 15.5 years) 66 suffered from irritable bowel syndrome with constipation and 62 from functional constipation. Demographic and physiological traits were similar in the two groups. Patients suffering from irritable bowel syndrome with constipation reported higher depression scores (18.8 ± 1.4 vs 12.7 ± 1.3, P=0.002) and higher symptom intensity scores for constipation (6.2 ± 0.3 vs 4.3 ± 0.4, P0.001), bloating (6.7 ± 0.3 vs 3.3 ± 0.4, P0.001) and abdominal pain (6.0 ± 0.3 vs 2.7 ± 0.4, P0.001) than patients with functional constipation. Multiple linear regression showed positive correlations between symptom intensity and depression and anxiety scores for functionally constipated patients only.Our results support the integration of a psychosocial component to the traditional treatment of constipated patients; however, further research exploring causality between psychosocial factors and specific gastrointestinal disorders would contribute to developing a tailored therapeutic approach. |
| Databáze: | OpenAIRE |
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