Primary biliary cirrhosis and myopathy: an uncommon association

Autor: Luiz Pedro Meireles, Bruno Cupertino Migueletto, Sueli K.N. Marie, Abrahão Elias Hallack Neto, Pedro Paulo Neves de Castro, Elaine Zamora Domingues, Hartmut Stocker, Milton Hideaki Arai
Rok vydání: 2000
Předmět:
Zdroj: Revista do Hospital das Clínicas, Vol 54, Iss 5, Pp 165-168
ISSN: 0041-8781
Popis: Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the majority of cases, muscular weakness has been interpreted as polymyositis. We report the case of a 48-year-old woman suffering from classic PBC, in association with a myopathy whose histological features are distinct from the cases reported before. We also performed a MEDLINE research for PBC and concomitant muscular diseases.
Databáze: OpenAIRE