Tuberculosis of the lumbar spine: outcomes after combined treatment of two-drug therapy and surgery
| Autor: | Oguz Karaeminogullari, Remzi A. Ozerdemoglu, Ufuk Aydinli, Cagatay Ozturk |
|---|---|
| Přispěvatelé: | Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı., Aydınlı, Ufuk |
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis medicine.medical_treatment Clinical article Spinal Tuberculosis Spondylitis Debridement Article Treatment duration Pharmacotherapy Deformity medicine Isoniazid Humans Orthopedics and Sports Medicine Spine fusion Kyphosis Rifampicin Antibacterial agent Aged Chemotherapy Short course chemotherapy Lumbar Vertebrae business.industry Follow up Middle Aged medicine.disease Combined Modality Therapy Surgery Management Orthopedics Lumbar spine Treatment Outcome Orthopedic surgery Spine stabilization Tuberculous spondylitis Female Tuberculosis Spinal business Anterior spine fusion medicine.drug Human |
| Zdroj: | Orthopedics. 30(1) |
| ISSN: | 0147-7447 |
| Popis: | This This article evaluates complications and treatment results in patienls with tuberculosis of the lurnbar spine. Eighteen patients with active tuerculosis of the lumbar spine were treated surgically in the orthopedic surgery department at Uludag University School of Medicine between 1993 and 2000. All patients received antituberculosis combination drug therapy (isoniazid and rifampicin) for 9 months. Patients who underwent anterior radical radical debridement and anterior fusion and/or posterolateral debridement and posterior fusion plus stabilization showed 5°-8° correction of local angulation after surgery. The mean loss of correction at final follow-up (mean: 5 years) in anterior or postierior surgery alone was 45%-5o%, whereas the corresponding finding for the combined approach was 12%. The combination of two-drug chemotherapy (daily isoniazid and rifampicin for 9 months) and surgery is effective for tuberculosis of the lumbar spine. |
| Databáze: | OpenAIRE |
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