Gynaecological cancers and their cell lines
| Autor: | Uroš Maver, Darja Arko, Kristijan Skok, Nejc Kozar, Lidija Gradišnik, Iztok Takač, Rajko Kavalar, Monika Sobočan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
tumour cell line endometrial neoplasms Genital Neoplasms Female MEDLINE Cell Culture Techniques Reviews Review Gynaecological cancer Bioinformatics cervix cancer 03 medical and health sciences 0302 clinical medicine breast neoplasm Cell Line Tumor Medicine Humans business.industry in vitro techniques gynaecology Cancer Cell Biology cell line medicine.disease 030104 developmental biology 030220 oncology & carcinogenesis Molecular Medicine pathology Female Cancer cell lines business |
| Zdroj: | Journal of Cellular and Molecular Medicine |
| ISSN: | 1582-4934 1582-1838 |
| Popis: | Cell lines are widely used for various research purposes including cancer and drug research. Recently, there have been studies that pointed to discrepancies in the literature and usage of cell lines. That is why we have prepared a comprehensive overview of the most common gynaecological cancer cell lines, their literature, a list of currently available cell lines, and new findings compared with the original studies. A literature review was conducted via MEDLINE, PubMed and ScienceDirect for reviews in the last 5 years to identify research and other studies related to gynaecological cancer cell lines. We present an overview of the current literature with reference to the original studies and pointed to certain inconsistencies in the literature. The adherence to culturing rulesets and the international guidelines helps in minimizing replication failure between institutions. Evidence from the latest research suggests that despite certain drawbacks, variations of cancer cell lines can also be useful in regard to a more diverse genomic landscape. |
| Databáze: | OpenAIRE |
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