Identification of bacteria using matrix-assisted laser desorption ionization time-of-flight mass spectrometry

Autor: Lisa M. Giaquinto, Jennifer A. Wagner, Sidney Pollack, Kevin B. Strunk, Mollie G. Kedney, Walter A. Patton
Rok vydání: 2011
Předmět:
Zdroj: Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. 35(6)
ISSN: 1470-8175
Popis: Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS or simply MALDI)1 has become ubiquitous in the identification and analysis of biomacromolecules. As a technique that allows for the molecular weight determination of otherwise nonvolatile molecules, MALDI has had a profound impact in the molecular biosciences, especially in the field of proteomics. MALDI analysis of whole organisms allows for the generation of a phenotypic profile or “molecular fingerprint;” once established, these fingerprints can be used for identification purposes.
Databáze: OpenAIRE