Tropylium tetrafluoroborate, a novel substrate for aldehyde oxidase
| Autor: | R. Bruce Banks, Stewart D. Barnett |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Xanthine Oxidase
Tropylium cation Biophysics Biochemistry Aldehyde Medicinal chemistry Catalysis Tropolone Substrate Specificity chemistry.chemical_compound Tropylium tetrafluoroborate Carbonium ion Organic chemistry Cycloheptanes Xanthine oxidase Molecular Biology Aldehyde oxidase chemistry.chemical_classification Iminium Cell Biology Aldehyde Oxidoreductases Aldehyde Oxidase Kinetics chemistry Tropone Oxidation-Reduction |
| Zdroj: | Biochemical and Biophysical Research Communications. 140:609-615 |
| ISSN: | 0006-291X |
| DOI: | 10.1016/0006-291x(86)90775-8 |
| Popis: | The stabilized carbonium ion salt, tropylium tetrafluoroborate, was oxidized to tropone (cycloheptatrienone) by rabbit liver aldehyde oxidase but not by the closely related molybdenum hydroxylase, xanthine oxidase. The tropylium cation is an aromatic hydrocarbon which lacks the aldehyde, imine, or iminium functional groups present in other substrates of aldehyde oxidase. The unique structural features of the tropylium ion should make it a useful tool for mechanistic studies of aldehyde oxidase. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|