Mechanical Circulatory Support for Cardiogenic Shock Complicating Acute Myocardial Infarction: An Experimental and Clinical Review
| Autor: | Marco Lanfranconi, Giuseppe Bruschi, Andrea Garatti, Emanuele Catena, Salvatore Trunfio, Filippo Milazzo, Paola Colombo, Ettore Vitali, Frigerio Maria, Tiziano Colombo, Claudio Russo |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Percutaneous medicine.medical_treatment Myocardial Infarction Shock Cardiogenic Biomedical Engineering Biophysics Bioengineering Intra-Aortic Balloon Pumping Biomaterials Internal medicine Fibrinolysis medicine Humans Myocardial infarction Survival rate business.industry Cardiogenic shock General Medicine medicine.disease Shock (circulatory) Cardiology Myocardial infarction complications Heart-Assist Devices medicine.symptom business |
| Zdroj: | ASAIO Journal. 53:278-287 |
| ISSN: | 1058-2916 |
| DOI: | 10.1097/mat.0b013e318057fae3 |
| Popis: | Cardiogenic shock (CS) occurs in 7% to 10% of cases after acute myocardial infarction and remains the most common cause of death in these patients. Despite aggressive treatment regimens such as fibrinolysis and percutaneous transluminal coronary angioplasty, mortality rates from CS remain extremely high. It has been shown that intra-aortic balloon pumping can result in initial hemodynamic stabilization. However, in the majority of studies, death was merely delayed. In recent years, efforts have been made to develop ventricular devices (LVAD) capable of providing complete short-term hemodynamic support. Seventeen major studies of LVAD support for CS complicating acute myocardial infarction are reported in the literature, with a mean weaning and survival rate of 58.5% and 40%, respectively. Patients considered in these studies are difficult to compare in terms of demographic and anatomic data, but taking these considerations into account, LVAD support seems to give no survival improvement in these patients compared with early reperfusion alone or associated with intra-aortic balloon pumping. Data emerging from experimental studies of acute myocardial infarction supported with LVAD are intriguing. In this review, we report the LVAD experience in the CS setting, starting from percutaneous extracorporeal support up to bridge therapy with implantable devices. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|