Assessment of the RIFLE criteria for the diagnosis of Acute Kidney Injury; a retrospective study in South-Western Ghana

Autor: Richard K. D. Ephraim, Enoch O. Antoh, Mabel Ephraim, Prince Adoba, Samuel Asamoah Sakyi, Kwame O. Darkwah
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: BMC Nephrology
ISSN: 1471-2369
Popis: Background Acute kidney injury (AKI) affects 3–7 % of patients admitted to the hospital and approximately 25–30 % of patients in the intensive care unit. RIFLE, a newly developed international consensus classification for AKI, defines three grades of severity—class R (risk), I (injury) and F (failure). The aim of this study was to evaluate whether the RIFLE system of classification can detect the incidence of AKI using retrospective data of in-patients at the Effia-Nkwanta Regional Hospital. Methods A total of 1070 in-patients’ records spanning a period of 6 months, from July 2014 to December 2014, was used. Demographic data and hospital admission serum creatinine of each participant were used for the calculation of estimated glomerular filtration rate (eGFR) using the 4-variable modification of diet in renal disease (MDRD) equation. Also, the baseline serum creatinine was estimated assuming a standard GFR of 75 ml/min/1.73 m2 using the simplified MDRD equation. Results Males had higher serum creatinine, eGFR, and baseline serum creatinine than females (P
Databáze: OpenAIRE