Use of methylphenidate for the management of fatigue in Chinese patients with cancer
| Autor: | TW Leung, Martin Law, Kin-Hoi Wong, Steven Wai Kwan Siu, Inda S. Soong, K. H. Ng, Annie O. L. Kwok, Po Tin Lam, Rico K. Y. Liu |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Severity of Illness Index Chinese version Neoplasms medicine Humans Prospective cohort study Fatigue Aged Brief Fatigue Inventory Aged 80 and over Methylphenidate business.industry Palliative Care Age Factors Cancer General Medicine Middle Aged medicine.disease Treatment Outcome Physical therapy Hong Kong Central Nervous System Stimulants Female business medicine.drug |
| Zdroj: | The American journal of hospicepalliative care. 31(3) |
| ISSN: | 1938-2715 |
| Popis: | Reason for the Study: Studies on methylphenidate for cancer-related fatigue showed conflicting results. This prospective study aims to determine whether methylphenidate is useful for relieving fatigue in Chinese patients with cancer. Chinese Version of Brief Fatigue Inventory (BFI-C) was administered on days 1, 8, and 29. Methylphenidate dose on day 1 was 5 mg daily then adjusted after day 8 according to response and side effects tolerance. Main Findings: Only 48% of the 25 recruited patients were on methylphenidate by day 29. Overall, no significant improvement in fatigue level was observed after methylphenidate, though benefits were shown in subgroups with age ≤ 65 and higher baseline BFI-C values. Principal Conclusions: Methylphenidate may be useful for management of cancer-related fatigue in selected Chinese patients. |
| Databáze: | OpenAIRE |
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