Enterovirus 68 among Children with Severe Acute Respiratory Infection, the Philippines
| Autor: | Hazel Galang, Naoko Fuji, Akira Suzuki, Raita Tamaki, Rapunzel Aniceto, Hitoshi Oshitani, Tadatsugu Imamura, Lydia Sombrero, S. Lupisan, Mariko Saito |
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| Rok vydání: | 2011 |
| Předmět: |
Male
Epidemiology viruses Philippines lcsh:Medicine medicine.disease_cause Polymerase Chain Reaction Severity of Illness Index law.invention Severe acute respiratory infection law Respiratory system Child Phylogeny Polymerase chain reaction Enterovirus D Human virus diseases human enterovirus D humanities Hospitalization Infectious Diseases Child Preschool Acute Disease Child Mortality Female Microbiology (medical) Adolescent enterovirus 68 Molecular Sequence Data Pneumonia Viral Enterovirus D macromolecular substances Biology lcsh:Infectious and parasitic diseases respiratory infections children Severity of illness Enterovirus Infections medicine Humans pneumonia lcsh:RC109-216 Research lcsh:R Infant Newborn Infant Sequence Analysis DNA medicine.disease Virology respiratory tract diseases Pneumonia Enterovirus Enterovirus 68 |
| Zdroj: | Emerging Infectious Diseases Emerging Infectious Diseases, Vol 17, Iss 8, Pp 1430-1435 (2011) |
| ISSN: | 1080-6059 1080-6040 |
| DOI: | 10.3201/eid1708.101328 |
| Popis: | TOC summary: Enterovirus 68 was found in 21 children with severe pneumonia. Enterovirus 68 (EV68) is a rare enterovirus associated with respiratory illness that, unlike other enteroviruses, has been identified only from respiratory specimens. We identified EV68 from respiratory specimens of children hospitalized with a diagnosis of severe pneumonia in Leyte, Republic of the Philippines. Twenty-one samples showed high similarity with EV68 by sequencing of 5′ nontranslated region; 17 of these samples were confirmed as EV68 by sequencing of viral protein 1 capsid coding region. Most previously reported EV68 cases had been identified as sporadic cases. All 21 patients we identified had severe illness, and 2 died, possibly the first reported fatal cases associated with EV68 infection. Our study suggests that EV68 may be a possible causative agent of severe respiratory illnesses. |
| Databáze: | OpenAIRE |
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