Predominant right ventricular dysfunction after right ventricular destruction in the dog
| Autor: | Jay N. Cohn, Constantinos J. Limas, Nabil H. Guiha |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
medicine.medical_specialty
Heart Ventricles medicine.medical_treatment Cautery Infarction Blood Pressure Blood volume Dogs Afterload Internal medicine medicine Animals Ventricular Function cardiovascular diseases Cardiac Output Blood Volume business.industry Myocardium Central venous pressure Anatomy medicine.disease medicine.anatomical_structure Ventricle Ventricular Fibrillation cardiovascular system Cauterization Ventricular pressure Cardiology Right Ventricular Free Wall Cardiology and Cardiovascular Medicine business Blood Flow Velocity |
| Zdroj: | The American Journal of Cardiology. 33:254-258 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/0002-9149(74)90284-7 |
| Popis: | Right and left ventricular function was assessed by observing the response to rapid blood volume expansion before and after extensive cauterization of the right ventricle in open chest dogs. In the control period, left ventricular end-diastolic pressure surpassed right ventricular end-diastolic pressure by an average of 11.5 mm Hg after volume expansion whereas, after destruction of the right ventricle, pressure in this chamber surpassed pressure in the left ventricle by an average of 4 mm Hg. In contrast, after left ventricular damage, left ventricular end-diastolic pressure averaged 25 mm Hg more than right ventricular end-diastolic pressure. Despite extensive damage to the right ventricular free wall, the right ventricle continued to generate a near normal pressure and aortic flow could be increased above control levels by volume expansion. We conclude that, in contrast to previous evidence, damage to the right ventricle produces a syndrome of predominant right ventricular dysfunction. However, cauterization of the entire free wall of the right ventricle does not reproduce the more profound right ventricular dysfunction noted in infarction of the right ventricle in man. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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