Investigating the potential of polymer gel dosimetry for interventional radiology: first results
| Autor: | P E Antoniou, Eleni Kaldoudi, R Sandaltzopoulos, P Bousbouras |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Materials science
Free Radicals Polymers medicine.medical_treatment Population Radiology Interventional Gel dosimetry chemistry.chemical_compound Organophosphorus Compounds medicine Dosimetry Radiology Nuclear Medicine and imaging Irradiation Radiometry education education.field_of_study Radiotherapy Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Dose-Response Relationship Radiation Magnetic resonance imaging Interventional radiology Equipment Design Magnetic Resonance Imaging Oxygen Radiation therapy Methacrylic acid chemistry Methacrylates Nuclear medicine business Gels |
| Zdroj: | Physics in Medicine and Biology. 53:N127-N136 |
| ISSN: | 1361-6560 0031-9155 |
| DOI: | 10.1088/0031-9155/53/8/n02 |
| Popis: | Complex interventional radiology (IR) procedures contribute an increasing percentage of the overall medical radiation exposure of the population making accurate dosimetry a challenge. Magnetic resonance (MR) based polymer gel dosimetry has been widely employed in complex dosimetric problems in radiotherapy. The aim of this note is to investigate the feasibility of normoxic gel dosimetry in IR. Dose response, energy dependence and dose rate dependence were investigated in irradiation set-ups relevant to IR for a particular normoxic gel, based on methacrylic acid (MAA) as the monomer and including tetrakis-hydroxy-methyl-phosphonium chloride (THPC) as antioxidant. The gel presents a linear dose response beyond a 25 cGy threshold. No significant energy dependence was observed in the useful range of interventional radiology (80-110 kVp). A linear correlation between the gel response and dose rate was observed in the range of dose rates relevant to IR (5-8 cGy min(-1)). These results demonstrate a reduction of gel sensitivity at very low dose rate levels. A possible explanation of this effect is suggested. |
| Databáze: | OpenAIRE |
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