Unilateral ovariectomy-induced luteinizing hormone-releasing hormone content changes in the two halves of the mediobasal hypothalamus
Autor: | Ida Gerendai, Claude Kordon, W.H. Rotsztejn, Umberto Scapagnini, Bianca Marchetti |
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Rok vydání: | 1978 |
Předmět: |
endocrine system
medicine.medical_specialty Mediobasal hypothalamus Chemistry General Neuroscience Ovary surgical procedures operative Endocrinology medicine.anatomical_structure Internal medicine polycyclic compounds medicine Unilateral Ovariectomy Luteinizing hormone hormones hormone substitutes and hormone antagonists Hormone |
Zdroj: | Neuroscience Letters. 9:333-336 |
ISSN: | 0304-3940 |
DOI: | 10.1016/0304-3940(78)90204-5 |
Popis: | The luteinizing hormone-releasing hormone (LHRH) content of the two halves of the mediobasal hypothalamus (MBH) has been studied two weeks after unilateral or bilateral ovariectomy (OVX) in the rat. In control animals, the LHRH content of the right-side MBH was higher than that of the left side. Right-side OVX induced a significant increase in LHRH content on the right-side MBH while left-side OVX was followed by elevated LHRH content on the left-side MBH. In contrast, bilateral OVX induced a significant decrease on the right-side MBH. The observation that unilateral OVX induced increased LHRH content in the ipsilateral half of the MBH to OVX, supports the view that a neural pathway might connect the ovary and the MBH. |
Databáze: | OpenAIRE |
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