Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study
| Autor: | Jia-Wei Lin, Tsai-Yuan Hsieh, Fang-Ying Su, Yu-Jung Chen, Gen-Min Lin, Yi-Hwei Li, Yen-Po Lin, Chih-Lu Han, Chih-Hung Wang, Yun-Shun Yu, Yu-Leung Shih, Felicia Lin, Kai-Wen Chen, Fan-Chun Meng |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Nonalcoholic steatohepatitis
Adult Male medicine.medical_specialty Hepatitis B virus Physical fitness Taiwan Hepacivirus Gastroenterology Chronic hepatitis B Body Mass Index 03 medical and health sciences Young Adult 0302 clinical medicine Hepatitis B Chronic Chronic hepatitis Retrospective Study Non-alcoholic Fatty Liver Disease Internal medicine medicine Prevalence Humans 030212 general & internal medicine Exercise Retrospective Studies Ultrasonography Hepatitis B Surface Antigens business.industry Alanine Transaminase General Medicine Cross-Sectional Studies Military Personnel Liver Military cohort 030211 gastroenterology & hepatology business Hepatitis A Virus Human |
| Zdroj: | World Journal of Gastroenterology |
| ISSN: | 2219-2840 1007-9327 |
| Popis: | AIM To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwanese military male cohort. METHODS We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study. Cases of chronic hepatitis B (n = 121) were defined by personal history and positive detection of hepatitis B surface antigen. Cases of nonalcoholic steatohepatitis (n = 129) were defined by alanine transaminase level > 60 U/L, liver ultrasound finding of steatosis, and absence of viral hepatitis A, B or C infection. All other study participants were defined as unaffected (n = 3419). Physical fitness was evaluated by performance in 3000-m run, 2-min sit-ups, and 2-min push-ups exercises, with all the procedures standardized by a computerized scoring system. Multiple linear regression analysis was used to determine the relationship. RESULTS Chronic hepatitis B negatively correlated with 2-min push-up numbers (β = -2.49, P = 0.019) after adjusting for age, service specialty, body mass index, systolic and diastolic blood pressures, current cigarette smoking, alcohol intake status, serum hemoglobin, and average weekly exercise times. Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time (β = 11.96, P = 0.084) and negatively correlated with 2-min sit-up numbers (β = -1.47, P = 0.040). CONCLUSION Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males, and future study should determine the underlying mechanism. |
| Databáze: | OpenAIRE |
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