A New Approach to the Synthesis of Optically Active Alkylated Adenine Derivatives
| Autor: | Evgeny F. Belanov, A. V. Shipitsyn, M. V. Jasko, N. F. Zakirova |
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| Rok vydání: | 2004 |
| Předmět: |
Alkylating Agents
Stereochemistry viruses Clinical Biochemistry Pharmaceutical Science Alkylation Biochemistry Chemical synthesis Antiviral Agents Drug Discovery Chlorocebus aethiops Animals Pox virus Nucleotide Molecular Biology Vero Cells chemistry.chemical_classification Chemistry Adenine Acyclic nucleoside Organic Chemistry Stereoisomerism General Medicine Optically active Nucleic acid Molecular Medicine Enantiomer Adenine derivatives |
| Zdroj: | ChemInform. 35 |
| ISSN: | 1522-2667 0931-7597 |
| DOI: | 10.1002/chin.200441199 |
| Popis: | A new synthesis of chiral acyclic nucleoside and nucleotide analogues starting from d (−)- or l (+)-riboses was proposed. Antiviral properties of the synthesized compounds towards the pox virus family were evaluated. |
| Databáze: | OpenAIRE |
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